{"id":49125,"date":"2026-09-30T09:17:33","date_gmt":"2026-09-30T07:17:33","guid":{"rendered":"https:\/\/www.emballagedigest.fr\/?p=49125"},"modified":"2026-10-05T09:19:40","modified_gmt":"2026-10-05T07:19:40","slug":"des-etiquettes-reduisent-la-penetration-doxygene-dans-les-seringues-coc","status":"publish","type":"post","link":"https:\/\/www.emballagedigest.fr\/en\/des-etiquettes-reduisent-la-penetration-doxygene-dans-les-seringues-coc\/","title":{"rendered":"Des \u00e9tiquettes r\u00e9duisent la p\u00e9n\u00e9tration d\u2019oxyg\u00e8ne dans les seringues COC"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Les seringues COC pr\u00e9remplies gagnent en importance pour le conditionnement des m\u00e9dicaments biologiques et biosimilaires modernes. Par rapport au verre, elles ont l\u2019avantage d\u2019\u00eatre plus l\u00e9g\u00e8res, plus r\u00e9sistantes \u00e0 la rupture, plus souples de conception en pr\u00e9sence de g\u00e9om\u00e9tries complexes, et de pr\u00e9senter une moindre adsorption des prot\u00e9ines. En revanche, leur perm\u00e9abilit\u00e9 aux gaz est plus \u00e9lev\u00e9e, ce qui peut entra\u00eener une p\u00e9n\u00e9tration accrue d\u2019oxyg\u00e8ne dans la seringue et compromettre la stabilit\u00e9 des principes actifs sensibles.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Pour relever ce d\u00e9fi, Schreiner MediPharm a d\u00e9velopp\u00e9 des \u00e9tiquettes fonctionnelles dot\u00e9es d\u2019une barri\u00e8re aux gaz int\u00e9gr\u00e9e. Elles r\u00e9duisent consid\u00e9rablement la p\u00e9n\u00e9tration d\u2019oxyg\u00e8ne et s\u2019adaptent en toute souplesse \u00e0 diff\u00e9rents types de seringues COC, sans modification aucun du conditionnement primaire ni des proc\u00e9d\u00e9s de production existants.<br>Schreiner MediPharm propose diff\u00e9rents concepts d\u2019\u00e9tiquette \u00e0 barri\u00e8re aux gaz int\u00e9gr\u00e9e. Gas-Protect-Label prot\u00e8ge une grande partie du corps de la seringue afin de r\u00e9duire la p\u00e9n\u00e9tration d\u2019oxyg\u00e8ne. Syringe-Closure-Wrap, qui enveloppe \u00e9galement le capuchon de la seringue, est pratiquement scell\u00e9e de mani\u00e8re \u00e9tanche aux gaz au niveau de l\u2019extr\u00e9mit\u00e9 sup\u00e9rieure et int\u00e8gre en outre une solution anti-effraction sous forme de t\u00e9moin de premi\u00e8re ouverture. Cette solution offre ainsi non seulement des fonctions de protection du principe actif, mais contribue \u00e9galement \u00e0 pr\u00e9server l\u2019int\u00e9grit\u00e9 du produit tout au long de la cha\u00eene d\u2019approvisionnement pharmaceutique.<br>L\u2019efficacit\u00e9 protectrice de ces \u00e9tiquettes \u00e0 fonction barri\u00e8re int\u00e9gr\u00e9e a \u00e9t\u00e9 \u00e9valu\u00e9e dans le cadre d\u2019\u00e9tudes externes men\u00e9es par<br>Prof. Dr. Sven S\u00e4ngerlaub \u00e0 l\u2019Universit\u00e9 de sciences appliqu\u00e9es de Munich (Hochschule M\u00fcnchen) ainsi que par un autre institut renomm\u00e9 dans le cadre d\u2019une mission d\u2019essai. La concentration d\u2019oxyg\u00e8ne dans des seringues COC purg\u00e9es \u00e0 l\u2019azote et ferm\u00e9es a \u00e9t\u00e9 mesur\u00e9e sans contact sur une p\u00e9riode prolong\u00e9e au moyen d\u2019un capteur optique d\u2019oxyg\u00e8ne. Les r\u00e9sultats montrent une r\u00e9duction significative de la p\u00e9n\u00e9tration d\u2019oxyg\u00e8ne. Sur une seringue Schott Toppac\u00ae de 1 ml, Gas-Protect-Label a multipli\u00e9 par sept environ le d\u00e9lai n\u00e9cessaire pour atteindre une concentration critique en oxyg\u00e8ne par rapport \u00e0 une seringue non \u00e9tiquet\u00e9e. Syringe-Closure-Wrap \u00e0 barri\u00e8re aux gaz int\u00e9gr\u00e9e a m\u00eame permis d\u2019obtenir un effet protecteur environ dix fois plus long.<\/p>","protected":false},"excerpt":{"rendered":"<p>Les seringues COC pr\u00e9remplies gagnent en importance pour le conditionnement des m\u00e9dicaments biologiques et biosimilaires modernes. Par rapport au verre, elles ont l\u2019avantage d\u2019\u00eatre plus l\u00e9g\u00e8res, plus r\u00e9sistantes \u00e0 la rupture, plus souples de conception en pr\u00e9sence de g\u00e9om\u00e9tries complexes, et de pr\u00e9senter une moindre adsorption des prot\u00e9ines. En revanche, leur perm\u00e9abilit\u00e9 aux gaz est [&hellip;]<\/p>","protected":false},"author":2,"featured_media":49126,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"iawp_total_views":0,"footnotes":""},"categories":[28,26,81,7,65],"tags":[],"class_list":["post-49125","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-article-entier","category-laterale","category-packaging","category-pharmacie","category-vu-dans-le-mag"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Des \u00e9tiquettes r\u00e9duisent la p\u00e9n\u00e9tration d\u2019oxyg\u00e8ne dans les seringues COC - Emballage Digest<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.emballagedigest.fr\/en\/des-etiquettes-reduisent-la-penetration-doxygene-dans-les-seringues-coc\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Des \u00e9tiquettes r\u00e9duisent la p\u00e9n\u00e9tration d\u2019oxyg\u00e8ne dans les seringues COC - Emballage Digest\" \/>\n<meta property=\"og:description\" content=\"Les seringues COC pr\u00e9remplies gagnent en importance pour le conditionnement des m\u00e9dicaments biologiques et biosimilaires modernes. Par rapport au verre, elles ont l\u2019avantage d\u2019\u00eatre plus l\u00e9g\u00e8res, plus r\u00e9sistantes \u00e0 la rupture, plus souples de conception en pr\u00e9sence de g\u00e9om\u00e9tries complexes, et de pr\u00e9senter une moindre adsorption des prot\u00e9ines. 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