Ultra-resistant freeze seal for pharmaceutical cartons

Schreiner MediPharm has developed a transparent seal designed for extreme environments, ensuring reliable adhesion down to -196°C for innovative medicines (mRNA-based drugs, biologics, and cell and gene therapies), while providing irreversible first-opening evidence through its “Multi-Tear” security system: any attempt to open the pack results in visible tearing of the film and potentially the carton fibers.

A complex guilloche pattern further enhances security, with the option to add additional overt, semi-covert, or covert features. Available in versions for application at 10°C and down to -50°C, the seal complies with regulatory requirements (EU Falsified Medicines Directive and ISO 21976 standard).